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glucocorticoid receptor

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Our Stolen Future: Arsenic is an endocrine disruptor
Inside the nucleus, arsenic interferes with the way that the glucocorticoid-receptor ... glucocorticoid-GR complex. The detailed mechanisms of the interference are not yet known. Glucocorticoid disruption by PCBs has already been documented, and appears to work because PCBs interfere with glucocorticoid-receptor ...
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Our Stolen Future: Disruption of hormone systems other than estrogen
PCB metabolites have been reported to bind to glucocorticoid receptors. More... At extremely low levels (10 ppb), arsenic inteferes with glucocorticoid-receptor control of DNA transcription. This may be ...
ourstolenfuture.org


Our Stolen Future: the glucocorticoid system
(GR), and the hormone-receptor complex formed when glucocorticoid binds with GR. Glucocorticoid enters the cell and binds with the GR. This hormone-receptor ...
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WSU IEHS Faculty Profile for Thomas Kocarek
Mol Pharmacol. 2005 Apr;67(4):1257-67. PMID: 15635043 Fang HL, Abdolalipour M, Duanmu Z, Smigelski JR, Weckle A, Kocarek TA, Runge-Morris M. Regulation of glucocorticoid ... M, Kocarek TA. CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor. Drug Metab Dispos. 2004 Jan;32(1):66 ...
www.iehs.wayne.edu


Our Stolen Future: A list of endocrine-disrupting compounds
Glucocorticoid Selective inhibition of DNA transcription normally stimulated by the glucocorticoid-GR complex. Kaltreider et al. 2001 Cadmium Estrogenic Activates estrogen receptor through an interaction with the hormone-binding domain of the receptor ...
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WSU IEHS Faculty Profile for Melissa Runge-Morris
Recently, her research group reported that glucocorticoid hormones and xenobiotics such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and ... M, Kocarek TA. CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor. Drug Metab Dispos. 2004 Jan;32(1): ...
www.iehs.wayne.edu